1bc8_C : 3D-footprint complex

structure name	STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS (PROTEIN SAP-1 ETS DOMAIN)
reference	Marmorstein et al. Mol.Cell 2 201 1998
source	Homo sapiens
experiment	X-ray (resolution=1.93, R-factor=0.220)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
multimeric complexes	1k6o_ABC
redundant complexes	1bc7_C 1k6o_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1bc8_C interface=57,58,61,62,64,65, mdsaitlwqfllqllqkpqnkhmicwtsndgqfkllqaeevarlwgirknkpnmnyDKlsRAlRYyyvkniikkvngqkfvykfvsypeilnm
interface signature	DKRARY

Estimated binding specificities ?

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# IC=4.894 IC/col=0.979 n_of_columns=5

specificity:

A |  19   0   0   0  20
C |  19   0  96  96   0
G |  19   0   0   0  76
T |  39  96   0   0   0

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Dendrogram of similar interfaces ?

matrix format

  
  ------QCKT--RGAT--RGNT--------   L         +-----------------------------8smh_F    
                                             ! 
  ------DCKT--RG----RGYA--KA----   L       +-3                            +5jvt_A    
                                           ! !       +--------------------1 
  ------DCKT--RGST--RGYA--------   L       ! +-------2                    +4bnc_A    
                                         +-4         ! 
  ----------RGNT--RGSTATRA------   L     ! !         +---------------------2o6g_G    
                                       +-5 ! 
  ------NCTTNA------VTNT--------   L   ! ! +-----------------------------1pp7_U    
                                     --6 ! 
  TT----KATTQTTG----LTRT--KAFTYT   L   ! +-----------------------------2p7c_B    
                                       ! 
  --KTHG------------------------       +-----------------------------5hdn_C

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updated Sat Jan 10 04:29:09 2026