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legend  pdf

structure nameSTRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS
(PROTEIN SAP-1 ETS DOMAIN)
referenceMarmorstein et al. Mol.Cell 2 201 1998
sourceHomo sapiens
experimentX-ray (resolution=1.93, R-factor=0.220)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyEtsdomain;
multimeric complexes1k6o_ABC
redundant complexes1bc7_C 1k6o_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDKRARY

Estimated binding specificities ?

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# IC=4.894 IC/col=0.979 n_of_columns=5 specificity:   
A |  19   0   0   0  20
C |  19   0  96  96   0
G |  19   0   0   0  76
T |  39  96   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ------QCKT--RGATRGNT------   L       +-----------------------------8smh_F    
                                     +-1 
  ------NCTTNA----VTNT------   L   +-2 +-----------------------------1pp7_U    
                                   ! ! 
  TT----KATTQTTG--LTRTKAFTYT   L --3 +-----------------------------2p7c_B    
                                   ! 
  --KTHG--------------------       +-----------------------------5hdn_C    
                                 

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updated Fri Sep 13 15:26:18 2024