3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYSTAL STRUCTURE OF CHYMOTRYPTIC FRAGMENT OF E. COLI SSB BOUND TO TWO 35-MER SINGLE STRAND DNAS
(SINGLE-STRAND DNA-BINDING PROTEIN)
referenceRaghunathan et al. Nat.Struct.Biol. 7 648 2000
sourceEscherichia coli
experimentX-ray (resolution=2.80, R-factor=0.256)
structural superfamilyNucleic acid-binding proteins;
sequence familySinglestrand binding protein family;
multimeric complexes1eyg_ABD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  RCVC--NC------RC----VCNCTCACSCECWCTCECWCRCFC--KCECVCECYC--------QC--RC------NCVC----TC--QC--                             +-1eyg_D    
                                                                                                        +------------------1 
  RT--KTNT----------------TTAT------TT--WTRT----RT--IT--YT----ET------RTWTYTTT----NT--NTMTQTLT   L   +--2                  +-6irq_A    
                                                                                                     !  ! 
  ----YT------------------------------------YGDG----------------ST--HT----------YT--RT--------   L --3  +--------------------3kjp_A    
                                                                                                     ! 
  --------DGTGFGYGKTYT----KG------------------------FG----IGHG--------------------------------   L   +-----------------------2i0q_A    
                                                                                                   

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updated Tue Dec 17 22:02:48 2024