2i0q_A : 3D-footprint complex

3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.

Dendrogram of similar interfaces ?

matrix format

structure name	CRYSTAL STRUCTURE OF A TELOMERE SINGLE-STRAND DNA-PROTEIN COMPLEX FROM O. NOVA WITH FULL-LENGTH ALPHA AND BETA TELOMERE PROTEINS (TELOMERE-BINDING PROTEIN ALPHA SUBUNIT)
reference	Horvath et al.
source	STERKIELLA NOVA
experiment	X-ray (resolution=1.91, R-factor=0.245)
structural superfamily	Nucleic acid-binding proteins;
sequence family	Telomerebinding protein alpha subunit, cen;
multimeric complexes	1otc_AB 2i0q_AB
redundant complexes	1otc
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2i0q_A interface=26,28,29,31,32,38,43,73,78,80,94,96,101,189,191,203,205,206,224,226,227,229,238,240,241,257,258,259, kyeyvelakasltsaqpqhfyavviDaTFpYKtnqerYicslKivdptlylkqqkgagdasdyatlvlyakrFedlpIiHragdiirvhratlRlYngqrQfnanvfyssswalfstdkrsvtqeinnqdavsdttpfsfsskhatiekneisilqnlrkwanqyfssysvissdmytalnkaqaqkgDfDvvakilqvhelDeYTnelklkdasgqvfytlsLkLKfPhvrtgevvRiRSatydetstqkkvlilSHYsniitfiqssklakelrakiqddhsvevaslkknvslnavvltevdkkhaalpstslqdlfhhadsdkelqaqdtfrtqfyvtkiepsdvkewvkgydrktkkssslkgasgkgdnifqvqflvkdastqlnnntyrvllytqdglganffnvkadnlhknadarkkledsaelltkfnsyvdavverrngfylikdtkliy

  
  ------DGTGFGYGKT--------YT----KG------------------------FG--IGHG--RGYGQG--------------DGDGDGYGTG--LGLGKGPGRGRGSG----------STHTYT--   L              +--------------------2i0q_A    
                                                                                                                                               +------2 
  ----------------STTT--DT------------------QC--HCFA--KT----------TGRAYCQCLG--KGDGQG------------------------------------------------   L       !      !            +-------1qzh_E    
                                                                                                                                             +-3      +------------1 
  ----KGFG--------ST--TTDT------------------TG--LAFA----------------QGYG--QGIA----------YT------------------------------------------   L     ! !                   +-------3kjp_A    
                                                                                                                                           +-4 ! 
  --------------------------------------------------------------------------------------QT--------RT----------LT--TTKT--FTQT------HT       ! ! +---------------------------4gnx_B    
                                                                                                                                         --5 ! 
  VCNC--------RC------------VCNCTCACSCTCECWC--RC----FC--ECVCYC----------------NCVC--TCQC--------------------------------------------   L   ! +----------------------------1eyg_D    
                                                                                                                                           ! 
  --------------------------------------------------------------------------------------------------------------------KTFT----------   L   +----------------------------6i52_B

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updated Tue Dec 17 22:49:23 2024