| structure name | COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA (FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12) |
| reference | Grant et al. |
| source | Mus musculus |
| experiment | X-ray (resolution=2.35, R-factor=0.215) |
| structural superfamily | C2H2 and C2HC zinc fingers; |
| sequence family | Zinc finger, C2H2 type; |
| multimeric complexes | 1f2i_GH 1f2i_IJ 1f2i_KL |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RDERRDH |
Estimated binding specificities ?
| readout + contact |  |
A | 19 0 0 0 19 0 C | 20 0 0 0 76 0 G | 19 96 96 96 0 96 T | 38 0 0 0 1 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: ZIF268 | ||
| GCGTGGGCG | PubMed | 1f2i_J(5.02e-05), 1f2i_IJ(2.72e-04), 1f2i_KL(3.21e-04) |
| GCGTGGGGCG | PubMed | 1f2i_J(8.62e-05) |
| AGCGTGGGCGT | PubMed | 1f2i_J(1.38e-04), 1f2i_IJ(2.45e-03), 1f2i_KL(2.79e-03) |
Dendrogram of similar interfaces ?
matrix format------HTHGRGTGTT--ACNA--KGRG L +1tf3_A +-1 --RGSTDAHARG--RGSTDCHG--TT-- L +----------2 +5kl3_A ! ! --QA--TCNA----QAHTTT----QA-- L +---4 +1g2d_F ! ! RGST--YGYC----QC--TGSTRGYT-- +--------5 +-----------4is1_C ! ! --LT--FCNA----QA--TTNA------ L ! ! +---1ubd_C --6 +-----------3 ----TCYCKARG--QA----TC------ ! +---5yeg_A ! --RG--DAQARG--RGSTDCHG--TT-- L +------------------------6b0o_A |
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updated Fri Sep 13 15:35:21 2024