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structure nameSTRUCTURE OF A CYS2HIS2 ZINC FINGER/TATA BOX COMPLEX (CLONE #2)
(TATA BOX ZINC FINGER PROTEIN)
referenceElrod-Erickson et al.
sourceMus musculus
experimentX-ray (resolution=2.20, R-factor=?)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
reference complex1g2f_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQTNQHTQTLHTDR

Estimated binding specificities ?

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# IC=12.600 IC/col=1.145 n_of_columns=11 specificity:   
A |  16   0   0   0   0  80   0  96   0   0   0
C |  16   0   0  16   0   0   0   0   0  96   0
G |  16   0   0   0   0   0   0   0  96   0  96
T |  48  96  96  80  96  16  96   0   0   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: FINGER
TAAAAAPubMed1g2d_F(4.86e-05)
AATAAAPubMed1g2d_F(4.40e-04)
AAAAAPubMed1g2d_F(2.93e-03)
term: TATA
TATAAAPubMed1g2d_F(3.63e-07)
TATAAAAGPubMed1g2d_F(1.26e-07)
TATAAAAPubMed1g2d_F(4.60e-09)
TATAAPubMed1g2d_F(5.30e-05)
TTTATAPubMed1g2d_F(3.63e-07)
TGTAAAPubMed1g2d_F(2.74e-03)
TATATAAPubMed1g2d_F(1.51e-04)
CATAAAAPubMed1g2d_F(1.12e-05)
CATAAAPubMed1g2d_F(4.40e-04)
TCACTATATATAGPubMed1g2d_F(3.33e-03)
TATAAGPubMed1g2d_F(4.47e-04)
ATATAAPubMed1g2d_F(4.47e-04)
TATATAPubMed1g2d_F(4.02e-03)
AATAAAAGPubMed1g2d_F(9.66e-05)
TATAAGCPubMed1g2d_F(3.20e-03)
TATAAGAGPubMed1g2d_F(5.58e-04)
TATAAATPubMed1g2d_F(1.14e-05)
CTATAAAAGPubMed1g2d_F(8.05e-10)
CATATAAPubMed1g2d_F(3.20e-03)
TTATATAPubMed1g2d_F(1.51e-04)
CGTATAACPubMed1g2d_F(1.10e-02)
TACAAAAGPubMed1g2d_F(6.48e-04)
CTTTTPubMed1g2d_F(8.27e-03)
TAAAAPubMed1g2d_F(5.20e-05)
TAAAAGCPubMed1g2d_F(3.17e-03)
TATAATPubMed1g2d_F(4.47e-04)
TATAGATAPubMed1g2d_F(6.24e-03)
TATAAACGPubMed1g2d_F(9.81e-05)
TAAAAGTPubMed1g2d_F(3.17e-03)
CATAAAACPubMed1g2d_F(9.66e-05)
TATCAAPubMed1g2d_F(2.48e-03)
TCTTATPubMed1g2d_F(2.57e-03)
TATAAGTPubMed1g2d_F(3.20e-03)
sitesourcematches (E-value)

Dendrogram of similar interfaces ?

matrix format
  
  ----KT--STHT----RG--DAQARG--RGSTDCHG--TT--   L   +-----------------------------6b0o_A    
                                                   !  
  ----QA--TCNA----QAHTTT--QA--TTLAHGTCDTRG--   L   !                                            +1g2d_F    
                                                   !                                       +----2 
  ----RA----NC------ATSGDCKG--DCPTSGSARTKG--   L   !                               +-------4    +2gli_A    
                                                   !                               !       ! 
  --NGKT--WTKG--------HTHGRGTGTT--ACNA--KGRG   L   !                             +-5       +-----1tf3_A    
                                                   !                             ! ! 
  ----RGSTDAHARG--RGSTDCHGTT--RG--DAEG--RG--   L   !                    +--------7 +-------------5kl3_A    
                                                   !                    !        ! 
  ----EC--SCKGRG--LT--FCNA----QA--TTNA------   L   !                    !        !          +----1ubd_C    
                                                   !                    !        +----------3 
  ----EC--SCKGRG----TCYCKARG--QA----TC------       !                    !                   +----5yeg_A    
                                                   !                 +-10  
  ----VT----NARG------ETTG----YG--ST--------       !                 !  !       +----------------6e94_A    
                                                 -17                 !  !     +-8 
  FA--RGSGSCTCTAHCQA--STDCKT--QASGSANAIGTT--   L   !                 !  !     ! !                +2kmk_A    
                                                   !                 !  !     ! +----------------1 
  ----EC--SGKGRG--DG--YCKGRG--QA----TC------   L   !              +-11  +-----9                  +5k5h_A    
                                                   !              !  !        ! 
  ----DA--SCHGRGRGDC--SCNA----NCKTSAHG--RG--   L   !              !  !        !   +--------------5ei9_F    
                                                   !              !  !        +---6 
  --------------RGST--YGYC----QC--TGSTRGYT--       !           +-12  !            +--------------4is1_C    
                                                   !           !  !  !  
  ----KG--WTKA--------HCHGRG--TA--ACNA--KGRG   L   !           !  !  +--------------------------1tf6_A    
                                                   !        +-13  !  
  ----RGSTDTEGRG--RGSGDCHGTT--RG--DAEG--RG--   L   !        !  !  +---------------------------4x9j_A    
                                                   !     +-14  !  
  --ITST--STHTRG--RG----EARA----TTTGEC--RG--   L   !     !  !  +---------------------------5v3j_F    
                                                   !  +-15  !  
  ----EC--SCKGRG----TCYCKARGTCQAST--TC------   L   !  !  !  +---------------------------5yef_B    
                                                   +-16  !  
  --RGDC--SCHG----DC--SANA----WC--SCVG--RG--   L      !  +---------------------------5v3g_A    
                                                      !  
  ----------YG----WT--WTSTET--FTVASGDCSART--   L      +---------------------------6a57_A    
                                                 

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updated Thu Sep 12 14:40:51 2024