1flo_A : 3D-footprint complex

structure name	FLP RECOMBINASE-HOLLIDAY JUNCTION COMPLEX I (FLP RECOMBINASE)
reference	Narendra et al. Mol.Cell 6 885 2000
source	Saccharomyces cerevisiae
experiment	X-ray (resolution=2.65, R-factor=0.254)
structural superfamily	DNA breaking-rejoining enzymes;lambda integrase-like, N-terminal domain;
sequence family	Recombinase Flp protein; Recombinase Flp protein Nterminus;
redundant complexes	1m6x_D 1p4e_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1flo_A interface=54,55,58,59,61,81,159,212,267,270,271,274, pqfdilcktppkvlvrqfverferpsgekialcaaeltylcwmithngtaikrATfmSYnTiisnslsfdivnkslqfkyKtqkatileaslkklipaweftiipyysditdivsslqlqfeskgnshskkmlkallsegesiweitekilnsfeytsRftktktlyqflflatfincgrfsdiknvdpksfklvqnkylgviiqclvtetKtsvsrhiyffsargridplvyldeflrnsepvlkrvnrtgnsssnkqeyqllkdNlvRSynKalkknapysifaikngpkshigrhlmtsflsmkglteltnvvgnwsdkttythqitaipdhyfalvsryyaydpiskemialkdetnpieewqhieqlkgsaegsirypawngiisqevldylssyinrri
interface signature	ATSYTKRKNRSK

Estimated binding specificities ?

readout + contact

# IC=6.857 IC/col=0.762 n_of_columns=9

specificity:

A |   0  42  33  24  24   0   0  96  96
C |   0  10  10  24  24   0   0   0   0
G |  96  21  21  24  24  96  96   0   0
T |   0  23  32  24  24   0   0   0   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --AATA--YGTTKGRAFCKCKC------NT----RGST--KT   L              +--------------------1flo_A    
                                                         +----1 
  --KATANA------------KT--------TT--STRGYC--           +-2    +--------------------1z1b_B    
                                                       ! ! 
  LTNTTT------------------TTQAATYG--YAKT----   L     +-3 +-------------------------5jk0_B    
                                                     ! ! 
  ------------------------------------RC----   L   +-4 +---------------------------6en2_A    
                                                   ! ! 
  ------------------------RT--ET------------     --5 +----------------------------6gys_E    
                                                   ! 
  ----------------------KA------RTLT----RT--   L   +----------------------------4e0p_A

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updated Tue Dec 19 05:38:13 2023