1h6f_B : 3D-footprint complex

structure name	HUMAN TBX3, A TRANSCRIPTION FACTOR RESPONSIBLE FOR ULNAR-MAMMARY SYNDROME, BOUND TO A PALINDROMIC DNA SITE (T-BOX TRANSCRIPTION FACTOR TBX3)
reference	Muller et al.
source	HOMO SAPIENS
experiment	X-ray (resolution=1.70, R-factor=0.201)
structural superfamily	p53-like transcription factors;
sequence family	Tbox;
multimeric complexes	1h6f_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1h6f_B interface=31,163,164,180,184, kddpkvhleakelwdqfhkrgtemvitksgRrmfppfkvrcsgldkkakyillmdiiaaddcrykfhnsrwmvagkadpempkrmyihpdspatgeqwmskvvtfhklkltnnisdkhgftilnsmhkyqprfhivrandilklpystfrtylfpetefiavTAyqndkitqlkidnnpFakgFrd
interface signature	RTAFF

Estimated binding specificities ?

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# IC=2.791 IC/col=0.399 n_of_columns=7

specificity:

A |  19  11   0  24  24  24  67
C |   9   9   0  24  24  24   9
G |  59   0  96  24  24  24   9
T |   9  76   0  24  24  24  11

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Dendrogram of similar interfaces ?

matrix format

  
  RGTTATFT--FG   L                       +1h6f_B    
                                       +-1 
  RGTTATFTACFG   L                   +-2 +6f59_B    
                                     ! ! 
  RGTCSCFT--FG          +------------3 +-2x6v_A    
                        !            ! 
  RGTC--FG--FT   L   +--4            +--5flv_I    
                     !  ! 
  RGTT--FG--FT     --5  +---------------5t1j_B    
                     ! 
  RGTTATFG--FG       +------------------4a04_B

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updated Sat Jan 10 04:38:47 2026