1h6f_B : 3D-footprint complex

structure name	HUMAN TBX3, A TRANSCRIPTION FACTOR RESPONSIBLE FOR ULNAR-MAMMARY SYNDROME, BOUND TO A PALINDROMIC DNA SITE (T-BOX TRANSCRIPTION FACTOR TBX3)
reference	Muller et al.
source	HOMO SAPIENS
experiment	X-ray (resolution=1.70, R-factor=0.201)
structural superfamily	p53-like transcription factors;
sequence family	Tbox;
multimeric complexes	1h6f_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1h6f_B interface=31,163,164,180,184, kddpkvhleakelwdqfhkrgtemvitksgRrmfppfkvrcsgldkkakyillmdiiaaddcrykfhnsrwmvagkadpempkrmyihpdspatgeqwmskvvtfhklkltnnisdkhgftilnsmhkyqprfhivrandilklpystfrtylfpetefiavTAyqndkitqlkidnnpFakgFrd
interface signature	RTAFF

Estimated binding specificities ?

contact

# IC=2.810 IC/col=0.401 n_of_columns=7

specificity:

A |   9  24  24  24   0  78  21
C |  11  24  24  24  96   9  57
G |   9  24  24  24   0   0   9
T |  67  24  24  24   0   9   9

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RGTTATFT--FG   L                       +1h6f_B    
                                       +-1 
  RGTTATFTACFG   L                   +-2 +6f59_B    
                                     ! ! 
  RGTCSCFT--FG          +------------3 +-2x6v_A    
                        !            ! 
  RGTC--FG--FT   L   +--4            +--5flv_I    
                     !  ! 
  RGTT--FG--FT     --5  +---------------5t1j_B    
                     ! 
  RGTTATFG--FG       +------------------4a04_B

home
updated Sun Aug 3 05:34:15 2025