1hlz_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT (ORPHAN NUCLEAR RECEPTOR NR1D1)
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=0.260)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	1a6y_AB 1ga5_AB 1ga5_EF 1hlz_AB
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hlz_B interface=24,27,31,32,79,81, gmvllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgR
interface signature	EKRRFR

Estimated binding specificities ?

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# IC=8.247 IC/col=0.825 n_of_columns=10

specificity:

A |  60  96  24  24  60   0   0   0   0  96
C |  12   0  24  24  12   0   0   0  96   0
G |  12   0  24  24  12  84  96   0   0   0
T |  12   0  24  24  12  12   0  96   0   0

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updated Sat Aug 2 00:57:21 2025