| structure name | 3D SOLUTION NMR STRUCTURE OF THE WILD TYPE HMG-BOX DOMAIN OF THE HUMAN MALE SEX DETERMINING FACTOR SRY COMPLEXED TO DNA (SEX-DETERMINING REGION Y PROTEIN) |
| source | HOMO SAPIENS |
| experiment | NMR |
| structural superfamily | HMG-box; |
| sequence family | HMG high mobility group box; |
| redundant complexes | 1j47 |
| reference complex | 1hry_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RNFIRNSSYP |
Estimated binding specificities ?
| contact |  |
A | 0 0 9 6 6 0 9 C | 0 1 6 6 6 0 6 G | 96 6 6 6 78 0 75 T | 0 89 75 78 6 96 6scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: SRY | ||
| AACAAT | PubMed | 1j46_A(3.38e-03), 1j47_A(1.12e-03) |
| AACAAAG | PubMed | 1j46_A(5.19e-05), 1j47_A(6.37e-06) |
| GAACAAT | PubMed | 1j46_A(1.05e-02), 1j47_A(3.38e-03) |
| ACAAT | PubMed | 1j46_A(1.01e-03), 1j47_A(3.55e-04) |
| GTTTGCACTTCGAAGCAGAG | PubMed | 1j46_A(7.47e-03), 1j47_A(7.92e-04) |
| CTTTG | PubMed | 1j46_A(1.01e-03), 1j47_A(3.59e-04) |
| ATTGTT | PubMed | 1j46_A(3.38e-03), 1j47_A(1.12e-03) |
| TCAAAG | PubMed | 1j46_A(3.38e-03), 1j47_A(1.13e-03) |
| NACAAT | PubMed | 1j46_A(3.38e-03), 1j47_A(1.12e-03) |
Dendrogram of similar interfaces ?
matrix formatRTNGFTIA--RA--NASGSTYAPG-- L +--1j46_A +-------------1 KCNT--MAMA--EGSAACNT----YT L +----2 +--2lef_A ! ! RCNTFTMA--RAHGNT--SAYA---- L +-3 +----------------3f27_D ! ! ----YC--VT----FC--SA------ L --4 +---------------------1ckt_A ! --STYGLASGLA--TGTCIT------ L +-----------------------3tq6_B |
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updated Sat Aug 2 01:00:12 2025