interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HMG1 DOMAIN A BOUND TO A CISPLATIN-MODIFIED DNA DUPLEX
(HIGH MOBILITY GROUP 1 PROTEIN)
referenceOhndorf et al. Nature 399 708 1999
sourceRattus norvegicus
experimentX-ray (resolution=2.50, R-factor=0.238)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYVFS

Estimated binding specificities ?

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# IC=2.960 IC/col=0.740 n_of_columns=4 specificity:   
A |   0   0  56  19
C |   0   0  14  38
G |  96  96  13  20
T |   0   0  13  19
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RC--YTMALTRA--VCTG--AAVCEC   L                      +--1qrv_A    
                                              +-------2 
  RCNTFTMA--RAHGNT----SA----   L              !       !  +3f27_D    
                                   +----------3       +--1 
  RC--FAFTCG----IC--VGAG----   L   !          !          +2gzk_A    
                                 --4          ! 
  RGNTFTMA--RT--NGRT--SA----   L   !          +----------7m5w_A    
                                   ! 
  ----YA--------FT----SG----       +---------------------5ze0_N    
                                 

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updated Fri Sep 13 15:29:32 2024