| structure name | GLUCOCORTICOID RECEPTOR MUTANT/DNA COMPLEX (GLUCOCORTICOID RECEPTOR) |
| reference | Gewirth et al. Nat.Struct.Biol. 2 386 1995 |
| source | Rattus norvegicus |
| experiment | X-ray (resolution=1.90, R-factor=?) |
| structural superfamily | Glucocorticoid receptor-like DNA-binding domain; |
| sequence family | Zinc finger, C4 type two domains; |
| multimeric complexes | 1lat_AB |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | EKAR |
Estimated binding specificities ?
| readout + contact |  |
A | 12 0 48 96 0 96 C | 12 0 12 0 96 0 G | 60 96 12 0 0 0 T | 12 0 24 0 0 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: GLUCOCORTICOID RECEPTOR | ||
| TGTTCT | PubMed | 1lat_A(1.42e-06), 1lat_AB(8.15e-05) |
| GGTACANNNTGTTCT | PubMed | 1lat_A(3.45e-04), 1lat_AB(6.68e-03) |
| TGTTCC | PubMed | 1lat_A(7.45e-11), 1lat_AB(4.63e-07) |
| GCTGTTCTGC | PubMed | 1lat_A(9.78e-05) |
| TGTTCANNNTGTTCT | PubMed | 1lat_A(4.86e-04), 1lat_AB(6.68e-03) |
| AGAACANNNTGTTCT | PubMed | 1lat_A(4.86e-04), 1lat_AB(6.68e-03) |
| GCAGAACAGC | PubMed | 1lat_A(9.78e-05) |
| AGAACA | PubMed | 1lat_A(1.42e-06), 1lat_AB(8.15e-05) |
Dendrogram of similar interfaces ?
matrix formatEAKG--KTRG-- L +2han_A +----1 ECKG--KGRG-- L +-----7 +2ff0_A ! ! ECKG--KGRG-- +------9 +----3dzy_A ! ! --KGVT--RG-- L ! ! +5cbz_E ! +----------2 EAKG--RTRTRT ! +4umm_E +--------12 ECKG--RGRG-- L ! ! +-----2nll_B ! ! +--------8 ECKG--KTRG-- L ! ! ! +-----2nll_A ! ! ! --KGVT--RG-- ! ! ! +-1r4i_A ! +-11 +-5 DGKG--RTRG-- L ! ! +--------6 +-3cbb_A -13 ! ! ! ECKG--RGRG-- L ! ! ! +-3dzy_D ! +--10 ETKGAT--RG-- L ! ! +1lat_A ! +---------4 ECKG--KGRG-- L ! ! +1ynw_B ! +-3 ECKG--RGRG-- L ! +5uan_B ! ECKA--RGRG-- L +---------------------------4nqa_I |
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updated Fri Sep 13 15:47:21 2024