interface graph thumbnail
legend  pdf

structure nameCYTOSINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE
(DNA POLYMERASE I)
referenceJohnson et al.
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=2.00, R-factor=0.239)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A;
multimeric complexes8scg_AD 8sci_AD 8scj_AD 8sck_AD 8scl_AD 8scm_AD 8scn_AD 8sco_AD 8scp_AD 8scr_AD 8scs_AD 8sct_AD 8scu_AD
reference complex4yfu_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTRNNYQH

Estimated binding specificities ?

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# IC=2.553 IC/col=0.638 n_of_columns=4 specificity:   
A |   0  24   0  16
C |   0  16  72   8
G |   0  48  16   8
T |  96   8   8  64
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updated Thu Jan 8 18:28:15 2026