interface graph thumbnail
legend  pdf

structure nameVND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, 20 STRUCTURES
(HOMEOBOX PROTEIN VND)
sourceDROSOPHILA MELANOGASTER
experimentNMR
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
redundant complexes1nk3_P
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRIQNYR

Estimated binding specificities ?

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# IC=4.516 IC/col=0.903 n_of_columns=5 specificity:   
A |   0   0  13  57  96
C |   0   0  57  13   0
G |  96   0  13  13   0
T |   0  96  13  13   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: VND
CAAGTGPubMed1nk3_P(2.17e-05)
AAGTGPubMed1nk3_P(2.09e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ------------RTQT--ITQANAVTKTKT   L                               +------------2ld5_A    
                                                                   ! 
  ------RA----------ITQTNAMG----   L                  +------------6             +5zjt_E    
                                                      !            !           +-1 
  ----RCRT----------NT--NAITRG--                      !            +-----------3 +5zjt_B    
                                                      !                        ! 
  --RC--RT----------ITQCNAACRG--   L              +---8                        +6a8r_A    
                                                  !   ! 
  ------------------IA--NA------                  !   !                         +4qtr_D    
                                                  !   !  +----------------------2 
  ------RT----------NT--NA------   L              !   !  !                      +1b72_B    
                                                +-9   +--7 
  ------------------NCITNARGRG--   L            ! !      !               +------6fqq_E    
                                                ! !      +---------------5 
  --------LTRTSGTGQTRG----------   L         +-10 !                      +------2xro_E    
                                             !  ! ! 
  --RT--RT--------KTIAQCNA----RT   L         !  ! +-----------------------------1ig7_A    
                                          +-11  !  
  ------RT----------IAKGNA------   L      !  !  +-----------------------------2hdd_A    
                                          !  !  
  RTTTAT--------NTTCTA----------   L   +-12  +-----------------------------5zux_A    
                                       !  !  
  ------RA--------KGSAQA--------   L   !  !                         +---6j5b_C    
                                     -13  +-------------------------4 
  ------RT--STVC--KGDCRG--------   L   !                            +---1w0t_A    
                                       !  
  ------RT----------NT--NA--RG--   L   +-----------------------------1b8i_B    
                                     

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updated Fri Sep 13 15:53:36 2024