interface graph thumbnail
legend  pdf

structure name8OXOGUANINE AT THE PRE-INSERTION SITE OF THE POLYMERASE ACTIVE SITE
(DNA polymerase I)
referenceBeese et al.
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=2.01, R-factor=0.194)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A;
multimeric complexes8scg_AD 8sci_AD 8scj_AD 8sck_AD 8scl_AD 8scm_AD 8scn_AD 8sco_AD 8scp_AD 8scr_AD 8scs_AD 8sct_AD 8scu_AD
reference complex4yfu_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRNNREYNQH

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |  13  13   0   0
C |  54  13  96   0
G |  16  16   0  96
T |  13  54   0   0
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updated Sat Aug 2 02:00:42 2025