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structure nameSTRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.
(NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC...)
referenceStroud et al. 'Cell(Cambridge,Mass.)' 126 375 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.238)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1a02_FJN 1p7h_LN 1pzu_BHIM 1s9k_CDE 2o93_LMO
reference complex3qrf_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRYTERQR

Estimated binding specificities ?

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# IC=6.322 IC/col=0.903 n_of_columns=7 specificity:   
A |  81   0   0  96  66  59  81
C |   7   0   0   0   7  16   7
G |   1  96  96   0  14   7   7
T |   7   0   0   0   9  14   1
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updated Thu Sep 12 15:56:32 2024