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legend  pdf

structure nameSTRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.
(NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC...)
referenceStroud et al. 'Cell(Cambridge,Mass.)' 126 375 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.238)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1a02_FJN 1p7h_LN 1pzu_BHIM 1s9k_CDE 2o93_LMO
reference complex3qrf_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRYTERQR

Estimated binding specificities ?

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# IC=3.664 IC/col=0.916 n_of_columns=4 specificity:   
A |  14   0   0   2
C |  28   1  95  89
G |  16   0   1   3
T |  38  95   0   2
scan!

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updated Thu Jan 8 19:47:40 2026