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structure nameSTRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.
(NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC...)
referenceStroud et al. 'Cell(Cambridge,Mass.)' 126 375 2006
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.238)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes1a02_FJN 1p7h_LN 1pzu_BHIM 1s9k_CDE 2o93_LMO
reference complex1p7h_L
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRYTERQR

Estimated binding specificities ?

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# IC=6.154 IC/col=0.879 n_of_columns=7 specificity:   
A |  73   0   0  96  68  73  73
C |   7   0   0   0   7   7   7
G |   7  96  96   0  14   7   7
T |   9   0   0   0   7   9   9
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updated Mon Dec 16 19:21:18 2024