| structure name | STRUCTURAL BASIS OF HETERODIMERIC ECDYSTEROID RECEPTOR INTERACTION WITH NATURAL RESPONSE ELEMENT HSP27 GENE PROMOTER (PROTEIN ULTRASPIRACLE) |
| reference | Kolodziejczyk et al. 'Nucleic 35 2705 2007 |
| source | DROSOPHILA MELANOGASTER |
| experiment | X-ray (resolution=1.95, R-factor=0.182) |
| structural superfamily | Glucocorticoid receptor-like DNA-binding domain; |
| sequence family | Zinc finger, C4 type two domains; |
| multimeric complexes | 1r0o_AB 2han_AB 4umm_AE |
| redundant complexes | 1r0o 4umm |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | EKKRR |
Estimated binding specificities ?
| readout + contact |  |
A | 12 0 0 0 0 60 C | 12 0 0 12 96 12 G | 60 96 0 0 0 12 T | 12 0 96 84 0 12scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: ECDYSTEROID RECEPTOR | ||
| AGGTCA | PubMed | 2han_A(6.84e-03), 1r0o_AB(6.75e-05) |
| GGTTCAATGCACT | PubMed | 2han_A(1.21e-07), 1r0o_AB(5.41e-03), 2han_AB(2.75e-13), ... (total=4) |
Dendrogram of similar interfaces ?
matrix formatECKA--RGRG-- L +-----------------------------4nqa_I ! ECKG--RGRG-- L ! +2nll_B ! +---------2 EAKG--RTRTRT ! ! +4umm_E ! +-------7 DGKG--RTRG-- L ! ! ! +3cbb_A ! ! +---------5 ECKG--RGRG-- L ! +-9 +3dzy_D ! ! ! EAKG--KTRG-- L ! ! ! +2han_A -13 ! ! +---------------1 ECKG--KGRG-- ! ! +--8 +3dzy_A ! ! ! ECKG--RGRG-- L ! +-10 +---------------5uan_B ! ! ! ECKG--KGRG-- L ! ! ! +1ynw_B ! ! ! +-3 --KGVT--RG-- ! ! ! +-4 +1r4i_A ! +-11 ! ! ! ETKGAT--RG-- L ! ! ! +------------------6 +1lat_A ! ! ! ! ECKG--KTRG-- L +---12 ! +-2nll_A ! ! --KGVT--RG-- L ! +----------------------5cbz_E ! ECKG--KGRG-- L +------------------------2ff0_A |
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updated Fri Sep 13 16:20:11 2024