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structure nameSTRUCTURE OF THE EPSTEIN-BARR VIRUS ZEBRA PROTEIN
(BZLF1 TRANS-ACTIVATOR PROTEIN)
referenceArtero et al. Mol.Cell 21 565 2006
sourceHUMAN HERPESVIRUS 4
experimentX-ray (resolution=2.25, R-factor=0.232)
structural superfamilyLeucine zipper domain;
sequence familybZIP transcription factor;
multimeric complexes2c9l_YZ 2c9n_YZ 5szx_AB 7nx5_AB
redundant complexes2c9n_Y 5szx_B 7nx5_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNAASR

Estimated binding specificities ?

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# IC=4.516 IC/col=0.903 n_of_columns=5 specificity:   
A |   0  13  96   0  13
C |   0  13   0  96  13
G |   0  57   0   0  13
T |  96  13   0   0  57
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ZEBRA
TGAGCCAPubMed2c9l_Z(6.10e-03), 2c9l_YZ(4.25e-07), 2c9n_YZ(4.09e-07), ... (total=5)
TGACATCAPubMed2c9l_Z(1.77e-03)
TGAGTCAPubMed2c9l_Z(7.17e-07), 2c9l_YZ(1.11e-12), 2c9n_YZ(1.05e-12), ... (total=5)
TGAGCAAPubMed2c9l_YZ(1.66e-03), 2c9n_YZ(2.29e-03), 5szx_AB(1.05e-02), ... (total=4)

Dendrogram of similar interfaces ?

matrix format
  
  ----NC----ATAT----STRG--   L                     +-----2c9l_Z    
                                       +-----------1 
  ------NCRT--ATAT----STRG         +---2           +-----1t2k_D    
                                   !   ! 
  ----NC----AAAT------RT--   L   +-3   +-----------------1a02_F    
                                 ! ! 
  NT----ATAT----STRG------   L --4 +---------------------1dh3_C    
                                 ! 
  --NC----AT------CTRA----       +-----------------------1s9k_E    
                               

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updated Fri Sep 13 16:14:07 2024