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structure nameSTRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
(AP-1 FRAGMENT FOS)
referenceGlover et al. Nature 392 42 1998
sourceHOMO SAPIENS
experimentX-ray (resolution=2.70, R-factor=0.246)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper;
multimeric complexes1a02_FJN 1s9k_CDE
redundant complexes1s9k
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNAAR

Estimated binding specificities ?

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# IC=3.673 IC/col=0.735 n_of_columns=5 specificity:   
A |  75   0   7  73  73
C |   7   0   7   9   7
G |   7   0  75   7   7
T |   7  96   7   7   9
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --NC----YGAT------RC------------   L         +---------------4eot_A    
                                               ! 
  --RC------NC----AAAT----CTRC----   L         !               +2wt7_A    
                                         +-----9           +---3 
  --RG------NC----YGAT----CTRG----   L   !     !  +--------6   +2wt7_B    
                                         !     !  !        ! 
  ----RA----NA----AAVT----STRG----   L   !     +--8        +---1h89_A    
                                         !        ! 
  --RG------NT----ATAT------RG----   L   !        !            +5vpe_C    
                                         !        +------------2 
  QG------QC----FTRC--------------   L -11                     +7aw7_D    
                                         !  
  --RA----NT----AAVT----STRG------   L   !              +------1hjb_A    
                                         !              ! 
  ------NC----AT------STRA--------       !    +---------7      +1a02_J    
                                         !    !         !   +--4 
  ----------NT----ATAT----STRG----   L   !    !         +---5  +1dh3_C    
                                         +---10             ! 
  ----------NCTT----AT------RG----   L        !             +--2dgc_A    
                                              !  
  ------------RA----NA----AAVTSTRG   L        !                +1nwq_C    
                                              +----------------1 
  ------NCRT--ATAT----STRG--------                             +1t2k_D    
                                       

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updated Thu Dec 22 17:17:44 2022