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structure nameSTRUCTURE OF TRANSCRIPTION FACTOR GENESIS/DNA COMPLEX
(PROTEIN TRANSCRIPTION FACTOR)
sourceRATTUS NORVEGICUS
experimentNMR
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQNSRHNSRR

Estimated binding specificities ?

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# IC=7.420 IC/col=0.742 n_of_columns=10 specificity:   
A |  19  63  63  34  96   0  92  96   4  70
C |  19  10  13  20   0   0   2   0  88   8
G |  20  13  10  20   0   0   1   0   2   8
T |  38  10  10  22   0  96   1   0   2  10
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: GENESIS
TATAAAAGPubMed2hdc_A(1.13e-02)

Dendrogram of similar interfaces ?

matrix format
  
  ------------------------RGHT--ST--------------------   L                                       +6akp_C    
                                                                                              +--2 
  ----------------NAST--RGHT--STLT--------------------   L                                    !  +7cby_C    
                                                                                           +--3 
  ----------------NA----RA--HT--STLT------------------   L                                 !  !  +2a07_J    
                                                                                      +----5  +--1 
  ------------------NAST--RG--------------------------   L                            !    !     +6nce_A    
                                                                                      !    ! 
  ----LT--NTHG--RT--YTPT------------------------------   L                     +------7    +------6qil_A    
                                                                               !      ! 
  ------ST----------NAST--RTHT--STLT------------------   L                     !      !    +------4lg0_A    
                                                                            +-10      +----4 
  PG--------------------------------------------------                      !  !           +------6la8_S    
                                                                            !  !  
  ----YC------HGQT--YTPT--------------LG--------------   L               +-11  +------------------5x11_A    
                                                                         !  !  
  --RTLT--NTHGTA----YTRG------------------------------   L               !  !      +-------------2efw_A    
                                                                      +-12  +------9 
  ----------PTPG--TTRG------------------HT------------   L            !  !         +-------------5xxp_A    
                                                                      !  !  
  ------ST----------NAST--RTHT--ST--------------------   L            !  !              +--------3l2c_A    
                                                                   +-13  +--------------6 
  --------------------------YG------------------------             !  !                 +--------4lb5_B    
                                                                   !  !  
  ----------NT--TCTA----------------------------------   L      +-14  !            +------------5zux_A    
                                                                !  !  +------------8 
  --------------------RC----YG------KT----------------          !  !               +------------2acj_B    
                                                             +-15  !  
  ----------------------------------------RGVGTGITPTRC   L   !  !  +---------------------------5v9x_A    
                                                           -16  !  
  --------------SGAA----------------------------------   L   !  +---------------------------6waa_D    
                                                             !  
  --------RC------------------------------------------   L   +-----------------------------7cc9_A    
                                                           

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updated Fri Sep 13 16:20:44 2024