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legend  pdf

structure nameGFI-1 ZINC FINGERS 3-5 COMPLEXED WITH DNA
(ZINC FINGER PROTEIN GFI-1)
sourceRATTUS NORVEGICUS
experimentNMR
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureFRSSTHQSDKQSSNT

Estimated binding specificities ?

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# IC=10.523 IC/col=1.052 n_of_columns=10 specificity:   
A |   0   0   8  96   8   0   0  96   0  56
C |   0   0  64   0   8   0   0   0   0  16
G |  96  96   8   0   8   0  96   0   0  16
T |   0   0  16   0  72  96   0   0  96   8
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: GFI-1
CCAATPubMed2kmk_A(4.12e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ----TTTGECRG--RG--ET----RGSCEC--RG--   L   +-----------------------------5v3j_F    
                                             ! 
  ------SA--MT--VT--NARG----ETTG------       !                            +--6e94_A    
                                             !            +---------------1 
  --EC--SGKGRG--DGYCKGRG--QA--TC------   L   !        +---2               +--5k5h_A    
                                             !        !   ! 
  --KG--WTKA------HCHGRG--TAACNA--KGRG   L --7     +--3   +------------------1tf6_A    
                                             !     !  ! 
  NGKT--WTKG------HTHGRGTGTTACNA--KGRG   L   !   +-4  +----------------------1tf3_A    
                                             !   ! ! 
  ------------RGSTYGYC----QCTGSTRGYT--       ! +-5 +-------------------------4is1_C    
                                             ! ! ! 
  --------------QA--TCRG--RGYCRT------   L   +-6 +--------------------------7txc_E    
                                               ! 
  QT--AG--KGRG--RGDCKG----------------   L     +---------------------------7n5w_A    
                                           

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updated Tue Dec 17 22:54:21 2024