7n5w_A : 3D-footprint complex

structure name	ZBTB7A ZINC FINGER DOMAIN BOUND TO DNA DUPLEX CONTAINING GGACCC (OLIGO 23) (Zinc finger and BTB domain-containing protein 7A)
reference	Horton et al. 'To ? ? ?
source	Homo sapiens
experiment	X-ray (resolution=2.24, R-factor=0.192)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
multimeric complexes	7n5v_AB
redundant complexes	7n5s_A 7n5t_A 7n5u_A 7n5v_A 8e3d_A 8e3e_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7n5w_A interface=16,20,23,45,47,48, lgsafqkcpicekviQgagKlpRhirthtgekpyecnickvrftRqDKlkvhmrkhtgekpylcqqcgaafahnydlknhmrvht
interface signature	QKRRDK

Estimated binding specificities ?

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# IC=5.937 IC/col=0.990 n_of_columns=6

specificity:

A |  16   0  80   0   0   0
C |  16   0  16  96  96  96
G |  16  80   0   0   0   0
T |  48  16   0   0   0   0

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Dendrogram of similar interfaces ?

matrix format

  
  QT--AG--KGRGRG--DCKG----   L                +----7n5w_A    
                                 +------------4 
  RGST--YGYC--QC--TGSTRGYT       !            +----4is1_C    
                                 ! 
  NGKT--WTKG------HTHG--RG   L --7                 +1tf3_A    
                                 ! +---------------3 
  --RGSTDAHARGRGSTDCHG--TT   L   ! !               +5kl3_A    
                                 ! ! 
  --QA--TCNA--QAHTTT----QA   L   +-6                 +1g2d_F    
                                   !               +-1 
  --RG--DAQARGRGSTDCHG--TT   L     !    +----------2 +6b0o_A    
                                   !    !          ! 
  --EC--SCKGRGLT--FCNA----   L     +----5          +1ubd_C    
                                        ! 
  --EC--SCKGRG--TCYCKA--RG              +-----------5yeg_A

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updated Wed Dec 18 09:51:38 2024