2ky8_A : 3D-footprint complex

structure name	SOLUTION STRUCTURE AND DYNAMIC ANALYSIS OF CHICKEN MBD2 METHYL BINDING DOMAIN BOUND TO A TARGET METHYLATED DNA SEQUENCE (METHYL-CPG-BINDING DOMAIN PROTEIN 2)
source	GALLUS GALLUS
experiment	NMR
structural superfamily	DNA-binding domain;
sequence family	MethylCpG binding domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 2ky8_A interface=22,30,44, dkqgrtdcpalppgwkkeeviRksglsagKsdvyyfspsgkkfRskpqlarylgnavdlscfdfrtgkmm
interface signature	RKR

Estimated binding specificities ?

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# IC=2.714 IC/col=0.678 n_of_columns=4

specificity:

A |  11   0   9   9
C |   9   0   9  69
G |   9  96  69   9
T |  67   0   9   9

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RGTTRT--YA--RG                                    +6d1t_A    
                                   +----------------1 
  RG------YCKARG                   !                +6cnp_A    
                       +-----------3 
  RG----DTYG--RT       !           !               +-6ogk_A    
                     --4           +---------------2 
  RG------YC--RG       !                           +-6c1y_A    
                       ! 
  RG----------RG       +-----------------------------6ccg_B

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updated Tue Dec 17 22:54:47 2024