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structure nameCRYSTAL STRUCTURE OF SV40 LARGE T ANTIGEN ORIGIN BINDING DOMAIN WITH DNA
(large T antigen)
referenceBullock et al. 'Plos 5 e23 2007
sourceSimian virus 40
experimentX-ray (resolution=2.40, R-factor=0.209)
structural superfamilyOrigin of replication-binding domain, RBD-like;
sequence familyOrigin of replication binding protein;
multimeric complexes2itl_AB 2ntc_AB 4fgn_AB 4gdf_AB 4gdf_EF 5d9i_AB
reference complex2itl_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSNRTR

Estimated binding specificities ?

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# IC=6.297 IC/col=0.900 n_of_columns=7 specificity:   
A |  73   7  75   0   0   0   7
C |   7   7   7   0   0  96  81
G |   7  75   7  88  96   0   1
T |   9   7   7   8   0   0   7
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updated Thu Jan 8 20:21:07 2026