3jtg_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MOUSE ELF3 C-TERMINAL DNA-BINDING DOMAIN IN COMPLEX WITH TYPE II TGF-BETA RECEPTOR PROMOTER DNA (ETS-related transcription factor Elf-3)
reference	Babayeva et al.
source	Mus musculus
experiment	X-ray (resolution=2.20, R-factor=0.234)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3jtg_A interface=56,57,60,61,63,64,78, gthlwefirdilihpelneglmkwenrhegvfkflrseavaqlwgqkkknsnmtyEKlsRAmRYyykreilervdgrRlvykfgknssgwkeeev
interface signature	EKRARYR

Estimated binding specificities ?

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# IC=6.860 IC/col=0.762 n_of_columns=9

specificity:

A |   0   0   0   0   0   8  24  11  12
C |  11   0  96  96   5  16  24  11  11
G |   6   0   0   0   0  56  24  12  11
T |  79  96   0   0  91  16  24  62  62

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: ELF3
AAGCAGGAAGTT	PubMed	3jtg_A(4.96e-10)

Dendrogram of similar interfaces ?

matrix format

  
  QCKT--RGAT--RGNT------   L         +-----------------------------8smh_F    
                                   +-1 
  ECKT--RGAT--RGNT------   L     +-2 +-----------------------------1pue_E    
                                 ! ! 
  DCKT--RG----RGYA----KA   L   +-3 +-----------------------------5jvt_A    
                               ! ! 
  DCKT--RGST--RGYA------   L --4 +-----------------------------4bnc_A    
                               ! 
  ----NAST--RGHT--STFT--   L   +-----------------------------1vtn_C

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updated Mon Jun 29 16:26:50 2026