3jtg_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF MOUSE ELF3 C-TERMINAL DNA-BINDING DOMAIN IN COMPLEX WITH TYPE II TGF-BETA RECEPTOR PROMOTER DNA (ETS-related transcription factor Elf-3)
reference	Babayeva et al.
source	Mus musculus
experiment	X-ray (resolution=2.20, R-factor=0.234)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Etsdomain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3jtg_A interface=56,57,60,61,63,64,78, gthlwefirdilihpelneglmkwenrhegvfkflrseavaqlwgqkkknsnmtyEKlsRAmRYyykreilervdgrRlvykfgknssgwkeeev
interface signature	EKRARYR

Estimated binding specificities ?

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# IC=6.079 IC/col=0.760 n_of_columns=8

specificity:

A |   7   0   0   0   0   7  24  14
C |   9   0  96  96   8  22  24  14
G |   7   0   0   0   0  45  24   9
T |  73  96   0   0  88  22  24  59

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: ELF3
AAGCAGGAAGTT	PubMed	3jtg_A(4.96e-10)

Dendrogram of similar interfaces ?

matrix format

  
  --KT--RG----RGYA------   L           +-----------------------------3wts_C    
                                     +-1 
  --------NT--CT--NGST--   L       +-2 +-----------------------------1if1_B    
                                   ! ! 
  ------TT----CT--NGKG--   L     +-3 +-----------------------------7rh2_B    
                                 ! ! 
  ----NAST--RGHT--STLT--   L   +-4 +-----------------------------7cby_C    
                               ! ! 
  ------TT----CT--NG----   L --5 +-----------------------------7oot_B    
                               ! 
  RC------------------SG       +-----------------------------7cow_T

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updated Fri Sep 13 17:19:08 2024