3lsr_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF DEST IN COMPLEX WITH DUPLEX DNA (DEST)
reference	Miller et al. Nat.Struct.Mol.Biol. 17 971 2010
source	PSEUDOMONAS AERUGINOSA
experiment	X-ray (resolution=2.55, R-factor=0.229)
structural superfamily	Homeodomain-like;
sequence family	Bacterial regulatory proteins, tetR family;
redundant complexes	3lsp_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3lsr_A interface=32,33,43,44,47, praeqkqqtrhalmsaarhlmesgrgfgslsLRevtraagivPAgfYrhfsdmdqlglalvaevdetfratlravrrnefelgglidasvrifldavganrsqflflareqyggslpirqaiaslrqritddlaadlallnkmphldgaaldvfadlvvktvfatlpelidppaakithqlrfimiggkhwh
interface signature	LRPAY

Estimated binding specificities ?

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# IC=4.471 IC/col=1.118 n_of_columns=4

specificity:

A |   0   0   0   9
C |  96   0   0   9
G |   0  96   0   9
T |   0   0  96  69

scan!

Dendrogram of similar interfaces ?

matrix format

  
  LTRG--PTAC--YT--   L                              +-3lsr_A    
                                     +--------------1 
  VT--AGDT--TTYTLA   L         +-----2              +-5gpc_B    
                               !     ! 
  ----TTRG----YTWA   L       +-3     +----------------7jnp_A    
                             ! ! 
  ----STVTAGTTFANT   L     +-4 +----------------------7amn_A    
                           ! ! 
  LC--RTPTPTSTYT--   L   +-5 +-----------------------6nsn_B    
                         ! ! 
  ----TGKG----YCFA   L --6 +-------------------------4pxi_B    
                         ! 
  MTRGTGPT--ATYTWT   L   +--------------------------5yej_B

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updated Sun Aug 3 07:13:35 2025