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structure nameTETR FAMILY TRANSCRIPTIONAL REGULATOR CIFR C99T-C181R CYSTEINES MUTANT COMPLEXED WITH 26BP DOUBLE-STRAND OPERATOR DNA
(Copper outer membrane regulator)
referenceMadden et al. 'To ? ? ?
sourcePseudomonas aeruginosa
experimentX-ray (resolution=2.60, R-factor=0.227)
structural superfamilyTetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence familyBacterial regulatory proteins, tetR family;
multimeric complexes6nsm_AB 6nsn_AB 6nsr_AB
redundant complexes6nsm_A 6nsr_M
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRLRPPSY

Estimated binding specificities ?

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# IC=8.912 IC/col=0.990 n_of_columns=9 specificity:   
A |  73   0   0  96   0  73  73  96   7
C |   9  96   0   0   0   7   7   0   7
G |   7   0   0   0   0   7   7   0   9
T |   7   0  96   0  96   9   9   0  73
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RT--LCRTPTPTSTYT----------------   L                                +6nsn_B    
                                                         +------------1 
  ------TTRG----YTWA--------------   L            +------2            +7jnp_A    
                                                  !      ! 
  ----------------QA--------------             +--3      +-------------3vok_A    
                                               !  ! 
  ----VTAGDT--TTYTLA--------------   L       +-4  +--------------------5gpc_B    
                                             ! ! 
  --RG--HCRGRG------QAQGKG--------   L   +---5 +-----------------------2glo_A    
                                         !   ! 
  ----TA--ECAC--YCRA--------------     --6   +------------------------5haw_A    
                                         ! 
  --------------------VT--KGDCRGTA   L   +----------------------------3sjm_A    
                                       

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updated Fri Sep 13 22:46:43 2024