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legend  pdf

structure nameMOLECULAR BASIS OF ENGINEERED MEGANUCLEASE TARGETING OF THE ENDOGENOUS HUMAN RAG1 LOCUS
(V2K7E-G19S)
referenceSubramanian et al. 'Nucleic 39 729 2011
sourceCHLAMYDOMONAS REINHARDTII
experimentX-ray (resolution=2.30, R-factor=0.182)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
multimeric complexes3mxb_AB 3mxb_RS
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSIQKRSNQSATYSVDRSKT

Estimated binding specificities ?

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# IC=10.911 IC/col=0.909 n_of_columns=12 specificity:   
A |   0   0   4  24   0   0   0  96   8   4  69  87
C |   0   0  13  24  96   0  96   0  19  10   4   0
G |   0  96   8  24   0   0   0   0  56  74  10   8
T |  96   0  71  24   0  96   0   0  13   8  13   1
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Dendrogram of similar interfaces ?

matrix format



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updated Fri Sep 13 17:30:03 2024