4efj_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF I-GZEII LAGLIDADG HOMING ENDONUCLEASE IN COMPLEX WITH DNA TARGET SITE (LAGLIDADG endonuclease)
reference	'To ? ? ? X-RAY DIFFRACTION
source	Gibberella zeae
experiment	X-ray (resolution=2.80, R-factor=0.188)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
redundant complexes	4z1x_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4efj_A interface=18,20,22,29,31,35,37,60,65,69,71,113,174,178,185,187,189,191,193,215,217,218,223,227,229, sinpwfvtgftdaegsfMiHlEknkdkwRvRptfQiKldirdkslleeiknyfnntgsiNtsnkEcvyKvRslkdisiiishfdkynlitqkkadfelfkkiinklnsqehlSyevgatvlqeiisirasmnlglsssvkedfphiipsnrplienmniphpewmagfvsgegSfsvYttsddkYvSlSfRvSqhnkdkqllksfvdffgcggfNyHNkgnkAvifVtRkfedindkiiplfneykikgvkykdfkdwskvakmieskshlttngykeickikenmnsyrk
interface signature	MHERRQKNEKRSSYYSSRSNHNAVR

Estimated binding specificities ?

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# IC=24.120 IC/col=1.149 n_of_columns=21

specificity:

A |   0   0   0   0   0  96   0   0  68   0  84   0   0   0   0   4  96   0  96  58  76
C |   0   0   0   0   0   0  96  96   8   0   4   0   0   0   0  12   0  96   0   8   8
G |   0  96  96  96   0   0   0   0  12   0   4   0   0  96  96   8   0   0   0  14   8
T |  96   0   0   0  96   0   0   0   8  96   4  96  96   0   0  72   0   0   0  16   4

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Dendrogram of similar interfaces ?

matrix format

  
  SGSTLGQG--YARGKGVT------HC--HG----QTRTDC--SANA----TASA--RGQGRG--------YC----RTEAVG   L                                 +4yis_A    
                                                                                                         +---------------1 
  ST--------RG--RC--ATVC------DC--YARTRGTAWGSAFC--RG----RGRGQG--EASCYT----RTWCQGRTEC   L   +-------------2               +7rcc_D    
                                                                                           !             ! 
  SGIGQAKGSC--RGQG--DGTAYC--AT--SCVCKGRG--------------------------------------------   L --3             +---------------6fb0_A    
                                                                                           ! 
  ----------------------------------------------DTYCNT----------------NG------------   L   +-----------------------------1r7m_B

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updated Mon Jun 29 17:47:09 2026