4efj_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF I-GZEII LAGLIDADG HOMING ENDONUCLEASE IN COMPLEX WITH DNA TARGET SITE (LAGLIDADG endonuclease)
reference	'To ? ? ? X-RAY DIFFRACTION
source	Gibberella zeae
experiment	X-ray (resolution=2.80, R-factor=0.188)
structural superfamily	Homing endonucleases;
sequence family	LAGLIDADG endonuclease;
redundant complexes	4z1x_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4efj_A interface=18,20,22,29,31,35,37,60,65,69,71,113,174,178,185,187,189,191,193,215,217,218,223,227,229, sinpwfvtgftdaegsfMiHlEknkdkwRvRptfQiKldirdkslleeiknyfnntgsiNtsnkEcvyKvRslkdisiiishfdkynlitqkkadfelfkkiinklnsqehlSyevgatvlqeiisirasmnlglsssvkedfphiipsnrplienmniphpewmagfvsgegSfsvYttsddkYvSlSfRvSqhnkdkqllksfvdffgcggfNyHNkgnkAvifVtRkfedindkiiplfneykikgvkykdfkdwskvakmieskshlttngykeickikenmnsyrk
interface signature	MHERRQKNEKRSSYYSSRSNHNAVR

Estimated binding specificities ?

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# IC=24.035 IC/col=1.145 n_of_columns=21

specificity:

A |   0   0   0   0   0  96   0   0  67   0  81   0   0   0   0   4  96   0  96  64  67
C |   0   0   0   0   0   0  96  96   4   0   4   0   0   0   0  14   0  96   0   4   9
G |   0  96  96  96   0   0   0   0   9   0   4   0   0  96  96   4   0   0   0  14   9
T |  96   0   0   0  96   0   0   0  16  96   7  96  96   0   0  74   0   0   0  14  11

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Dendrogram of similar interfaces ?

matrix format

  
  SCMCRG----YTSTECTT--RG--TTRG--WTTTHGYCRGRGIT----QCKA----MCHTTGKT   L                           +5thg_A    
                                                                         +-----------------------1 
  SA--RARG----ECECKG--ST--ATRGRGWGCAFTQACT--SA--YTLA----FTWCEATT--   L   !                       +6uw0_B    
                                                                       --3 
  SA--RGRGSTSTECQGTA--ST--AT--KG--CAFCQAQA----TAYAKG--KGFTWCEATA--   L   !      +----------------4yhx_A    
                                                                         +------2 
  SGIGQAKG--KG--KGTAYC--STVG--YA----------------------------------   L          +----------------6fb0_B

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updated Sat Jan 10 06:57:30 2026