| structure name | TERNARY COMPLEX OF BLOOM'S SYNDROME HELICASE (Bloom syndrome protein) |
| reference | Bertrand et al. 'Acta 70 1465 2014 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.30, R-factor=0.183) |
| structural superfamily | P-loop containing nucleoside triphosphate hydrolases;HRDC-like; |
| sequence family | RQC domain; DEAD/DEAH box helicase; Helicase conserved Cterminal domain; HRDC domain; |
| redundant complexes | 4cgz_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Dendrogram of similar interfaces ?
matrix format------------------------------------------IC----KC----RTLC--MTEC------------------ST----------------------------NGAGNGDTQG------ +----4o3m_A +--------------2 ------------------------------------------VC----KC------MCVC----EC-------------------------------------------------------------- +---7 +----4u7d_A ! ! ----------ET------NGRGSG------------------IC----KCHTTGRCLC---------------------------------------------------------------------- +--9 +-------------------7aud_E ! ! ----RTQT----EG--------------CGNCSG--KG------DG--RG------------------------------------------------------------------------------ L +-12 +-----------------------6crm_A ! ! ----------------HA------------------------NT------------------------------------------------------------------------------------ +-14 +--------------------------6znp_A ! ! --RC------HC--------------QT---------------------------------------------------------------------------------------------------- +-17 +---------------------------6m6b_M ! ! ------------------------------------------RG------------------------------------------------------------------------------------ ! +----------------------------6ftx_W +-18 ------------------------RT----------------SC----PG------------------------------------------------------------------------------ L ! ! +-------------------------5v9x_A ! ! +-10 --------------RC---------------------------------------------------------------------------------------------------------------- ! ! ! +-------------------------1z63_A ! +-16 RA------RT------------------------RA--AA--PA--RT-------------------------------------------------------------------------------- ! ! +-----------------2p6r_A ! ! +---------6 ------------------------------------------IC------------------------------------------------------------------------------------ L ! +-15 +-----------------5n8r_B ! ! ----------QG-------------------------------------------------------------------------------------------------------------------- ! +---------------------------6gen_M ! --------------------------------------------------------------------------KAFA------------------------------------YA--NAKTFGMC-- +-19 +------------3aaf_B ! ! +----4 --------------------------------------------------------------------QA---------------------------------------------------------- ! ! ! +------------7k63_U ! ! +-------5 --------------------------------------------------------------------------------------------NASTRGHT----STLT-------------------- L ! ! ! ! +7cby_C ! ! ! +----------------1 --------------------------------------------------------------------------------YC--KTHGSTQTYTPT------------------------LG------ L ! ! +-11 +5x11_A ! ! ! ! --------------------------------------------------------------------------------------------NASTRTHT----STLT-------------------- L +-20 ! ! ! +--------------------4lg0_A ! ! ! ! +----8 ------------------------------------------------------------------------------TT--------KATTQTTG--LTRT------KA------------FT--YT L ! ! +-13 ! +-----2p7c_B ! ! ! +--------------3 ----------------------------------------------------------------------RT--------LT--NTHGTA--YTRG------------------------QA------ ! ! ! +-----2efw_A +-21 ! ! ----------------------------------------------------------------------------------------------RC--YG----------KT---------------- ! ! ! +---------------------------2acj_B ! ! ! --------------------------------------SGKT-------------------------------------------------------------------------------------- +-22 ! +-----------------------------7amv_W ! ! ! ------------------------------------------------------------------RT--------------------VT--KGDC--RGTA-------------------------- ! ! +-----------------------------7c4p_A -23 ! ------------------------------------------------------------------RA------------------------KGSA----QAKT------------------------ L ! +-----------------------------7d3t_D ! ------------------------------RT------------------------------------------------------------------------------------------------ L +-----------------------------6ppr_B |
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updated Fri Sep 13 18:33:49 2024