interface graph thumbnail
legend  pdf

structure nameA NEW BIO-ISOSTERIC BASE PAIR BASED ON REVERSIBLE BONDING
(DNA POLYMERASE)
referenceTomas-Gamasa et al. 'Angew. 54 796 2015
sourceGEOBACILLUS STEAROTHERMOPHILUS
experimentX-ray (resolution=2.00, R-factor=0.180)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A;
multimeric complexes8scg_AD 8sci_AD 8scj_AD 8sck_AD 8scl_AD 8scm_AD 8scn_AD 8sco_AD 8scp_AD 8scr_AD 8scs_AD 8sct_AD 8scu_AD
reference complex4yfu_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRNNYQH

Estimated binding specificities ?

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# IC=2.714 IC/col=0.678 n_of_columns=4 specificity:   
A |   9   9   9   0
C |  69  67  69   0
G |   9  11   9   0
T |   9   9   9  96
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updated Sat Aug 2 07:18:41 2025