| structure name | STRUCTURE OF E2F8, AN ATYPICAL MEMBER OF E2F FAMILY OF TRANSCRIPTION FACTORS (Transcription factor E2F8) |
| reference | Morgunova et al. 'Nat 6 10050 2015 |
| source | Homo sapiens |
| experiment | X-ray (resolution=3.07, R-factor=0.272) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | E2F/DP family wingedhelix DNAbinding domai; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RERRRYTRRY |
Estimated binding specificities ?
| readout + contact |  |
A | 12 0 0 0 0 0 0 64 C | 21 74 96 96 0 96 96 10 G | 10 1 0 0 96 0 0 12 T | 53 21 0 0 0 0 0 10scan! |
Dendrogram of similar interfaces ?
matrix formatRC----EGRTRGRGYT--------------TG--RGRGYC-------- L +-----------------4yo2_A +-----4 ----------------------------RC----------------SG +-5 +-----------------7cow_T ! ! --ETNTSCRGHC--RT--------QA---------------------- +-6 +-----------------------5d4s_B ! ! --------------------------------------------NG-- +-7 +-------------------------7k63_U ! ! --------------------------RC-------------------- +-8 +--------------------------6l9z_S ! ! ----------------RCYG--KT------------------------ ! ! +------2acj_B ! +--------------------2 --------------------------------NTTCTA------RT-- L +-9 +------5zux_A ! ! ------------------YGRG-------------------------- ! ! +-4wcg_A ! ! +---------1 ----RAST--ECTTRAKA------HT---------------------- -10 +----------------3 +-7oz3_B ! ! --EGRGSARGMCTTRT-------------------------------- L ! +-----------4wwc_B ! ----------------------------------NASTRTHTST---- +----------------------------3co7_C |
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updated Fri Sep 13 19:04:06 2024