4wwc_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF FULL LENGTH YVOA IN COMPLEX WITH PALINDROMIC OPERATOR DNA (HTH-type transcriptional repressor YvoA)
reference	Fillenberg et al. 'Nucleic 43 1283 2015
source	Bacillus subtilis
experiment	X-ray (resolution=2.90, R-factor=0.234)
structural superfamily	Chorismate lyase-like;"Winged helix" DNA-binding domain;
sequence family	UTRA domain; Bacterial regulatory proteins, gntR family;
multimeric complexes	4wwc_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4wwc_B interface=38,39,48,49,50,51,53, hmninkqspipiyyqimeqlktqikngelqpdmplpsEReyaeqfgiSRMTvRqalsnlvnegllyrlkgrgtfvskpkmeqgltsftedmksrgmtpgsrlidyqlidseelaailgcgpssihkitrvrlandipmaiesshipfelagelnesiydhierynsipisrakqelepsaatteeanilgiqkgapvllikrttylqngtafehaksvyrgdrytfvhymd
interface signature	ERSRMTR

Estimated binding specificities ?

readout + contact

# IC=8.820 IC/col=0.588 n_of_columns=15

specificity:

A |   0  57  48  24  24  24  24  24   0  96  24  96   0   0  61
C |  96   6   6  24  24  24  24  24   0   0  24   0  96  96   9
G |   0  13  22  24  24  24  24  24   0   0  24   0   0   0  13
T |   0  20  20  24  24  24  24  24  96   0  24   0   0   0  13

scan!

Dendrogram of similar interfaces ?

matrix format

  
  EGRGSARGMCTTRT----------   L               +------------------4wwc_B    
                                       +-----1 
  ETNTSCRGHC--RT--------QA           +-2     +------------------5d4s_B    
                                     ! ! 
  --------------RCYG--KT--         +-3 +------------------------2acj_B    
                                   ! ! 
  ----------------YGRG----       +-4 +--------------------------4wcg_A    
                                 ! ! 
  --------TTHT--KG------RC   L --5 +---------------------------7b0c_A    
                                 ! 
  RA--ST--ECTTRAKA------HT       +---------------------------7oz3_B

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updated Tue Dec 19 09:38:25 2023