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3D-footprint cannot reliably estimate the specificity of 'Nucleic acid-binding proteins', as they bind to single-stranded DNA and thus accumulate more base contacts.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYO-EM STRUCTURE OF MCM2-7 DOUBLE HEXAMER ON DSDNA
(DNA REPLICATION LICENSING FACTOR MCM4)
sourceSACCHAROMYCES CEREVISIAE
experimentNMR
structural superfamilyNucleic acid-binding proteins;P-loop containing nucleoside triphosphate hydrolases;
sequence familyMCM2/3/5 family; ATPase family associated with various cellul;
multimeric complexes5bk4_234567ABCDEF 5u8s_25 5u8s_3467 6f0l_234567ABCDEF 6sko_234567 6wgg_49ABCDE 6wgi_346 6wgi_79BCDE 7p30_234567ABCDEF
redundant complexes5u8s 6f0l 6sko 6wgg 6wgi 7p30
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  ----------------------------------------------RG----------------------                                     +-----5bk4_C    
                                                                                                 +-----------2 
  ----------------------------------------------------------------KT----                    +----3           +-----6raw_5    
                                                                                            !    ! 
  ----------------------------------------------------------------RT----                  +-4    +-----------------6u0m_5    
                                                                                          ! ! 
  ----------------------------------------------------------------KT--WT                +-5 +----------------------6u0m_2    
                                                                                        ! ! 
  ------------------------------------------------------------------DA--              +-6 +------------------------6u0m_3    
                                                                                      ! ! 
  ----------------------------------------------------------------VT----            +-8 +-------------------------6raw_3    
                                                                                    ! ! 
  ----------------------------------------------LT----------------------          +-9 +--------------------------6raw_4    
                                                                                  ! ! 
  ----------------------------------------------------------------KA----       +-10 +---------------------------5v8f_2    
                                                                               !  !  
  --RTETKT----RTMT--RTFT----------------------------RT------------------   L   !  !   +-------------------------4pog_H    
                                                                               !  +---7 
  ------------TT--AT--FTNT----------------------------------------------   L -11      !                      +--6bhx_B    
                                                                               !      +----------------------1 
  ----------------VT--FT--RTFTITYT--RT--ET--WT------RT----QTFTDTKT------   L   !                             +--2vw9_A    
                                                                               !  
  RTCT--KTLTNTRT----------------YTRT--HTRTKT--WT--QTETITST--------------   L   +-----------------------------3ulp_D    
                                                                             

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updated Tue Dec 19 10:06:06 2023