interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF AQUIFEX AEOLICUS SIGMAN BOUND TO PROMOTER DNA
(RNA polymerase sigma factor RpoN)
referenceRajashankar et al. 'Proc. 114 E1805 2017
sourceAquifex aeolicus (strain VF5) / Aquifex aeolicus (strain VF5)
experimentX-ray (resolution=3.40, R-factor=0.291)
structural superfamily"Winged helix" DNA-binding domain;Sigma3 and sigma4 domains of RNA polymerase sigma factors;
sequence familySigma54, DNA binding domain; Sigma54 factor, core binding domain 572;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRESSRRRTR

Estimated binding specificities ?

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# IC=11.137 IC/col=0.796 n_of_columns=14 specificity:   
A |   0  96  57   0  13  24  24  24  24   0   0   0   0  96
C |  96   0  13   0  13  24  24  24  24   0   0  96  96   0
G |   0   0  13   0  16  24  24  24  24   0  96   0   0   0
T |   0   0  13  96  54  24  24  24  24  96   0   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------------------RAETSCSTRT--RGRGTT--RT   L          +-----------------------5ui5_I    
                                                       +--1 
  ------------------------------DTRGRCTTKTRT   L     +-2  +-----------------------2o9l_A    
                                                     ! ! 
  --------------YGRG------------------------       +-3 +--------------------------4wcg_A    
                                                   ! ! 
  ------------RCYG--KT----------------------     --4 +----------------------------2acj_B    
                                                   ! 
  ETNTSCRGHCRT------------------------------       +----------------------------5d4s_B    
                                                 

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updated Wed Dec 18 02:24:07 2024