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structure nameCRYSTAL STRUCTURE OF MUTANT ORR3 IN COMPLEX WITH NTD OF ARAR
(Arabinose metabolism transcriptional repressor)
referenceNair et al. 'Nucleic 41 639 2013
sourceBacillus Subtilis
experimentX-ray (resolution=1.97, R-factor=0.221)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyBacterial regulatory proteins, gntR family;
multimeric complexes4egy_AB 4egz_AB 4h0e_AB 5d4r_AB 5d4s_AB
redundant complexes4egy_B 4egz_A 5d4r_B 5d4s_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureENSRHRQ

Estimated binding specificities ?

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# IC=4.337 IC/col=0.723 n_of_columns=6 specificity:   
A |   0  12  24  48   0  96
C |  96  12  24  12  96   0
G |   0  48  24  12   0   0
T |   0  24  24  24   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: AraR
ATTTGTACPubMed4h0e_A(1.62e-03), 4egy_AB(4.13e-03), 4h0e_AB(1.13e-02), ... (total=4)

Dendrogram of similar interfaces ?

matrix format
  
  VTSARGTA----RT------------   L             +-----------------------------6za3_B    
                                           +-1 
  --ITRGECSC--SGKG----------   L         +-2 +-----------------------------5i2d_R    
                                         ! ! 
  --EGRTRGRG--YT------------   L       +-3 +-----------------------------4yo2_A    
                                       ! ! 
  --------------------YG----         +-4 +-----------------------------3eyi_B    
                                     ! ! 
  ------------NAST--RTHTST--   L   +-5 +-----------------------------3l2c_A    
                                   ! ! 
  --RG----DTVT----ST------WT   L --6 +-----------------------------6lxn_A    
                                   ! 
  --------SA----------------       +-----------------------------2xcr_U    
                                 

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updated Fri Sep 13 18:18:27 2024