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structure nameREF6 ZNF2-4-NAC004-MC3 COMPLEX
(Lysine-specific demethylase REF6)
referenceYao et al. 'Nat 10 2063 2019
sourceArabidopsis thaliana
experimentX-ray (resolution=2.05, R-factor=0.201)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes6jnn_AN
redundant complexes6jnl_A 6jnn_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureFKYWWSEFVSDSR

Estimated binding specificities ?

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# IC=5.957 IC/col=0.851 n_of_columns=7 specificity:   
A |  38  92   0  96  24  81   0
C |  19   2  96   0  24   4   0
G |  19   1   0   0  24   7  96
T |  20   1   0   0  24   4   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --QA--TTNA--STQAQTATSTNTAT--TTLAHGTCRG--   L                                  +1g2f_F    
                                                                     +----------1 
  --------KG--------HTHG--RGTGTT--ACNAKGRG   L     +-----------------3          +1tf3_A    
                                                   !                 ! 
  RGST--YGYC----QC--TGSTRGYT--------------       +-5                 +-----------4is1_C    
                                                 ! ! 
  --------------RG--DGEC--RG--RGSGDCHA----   L   ! !                          +--2wbs_A    
                                               --6 +--------------------------2 
  --------------QA----TC--RG--RG--YCRT----   L   !                            +--7txc_E    
                                                 ! 
  --NT--STNAVT--QTSTSGKG--RG--------------   L   !                +------------6u9q_A    
                                                 +----------------4 
  QT--AG--KGRG--RG--DCKG------------------   L                    +------------7n5w_A    
                                               

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updated Fri Sep 13 22:12:38 2024