6fzt_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SMAD8_9-MH1 BOUND TO THE GGCGC SITE. (Mothers against decapentaplegic homolog 9)
reference	Kaczmarska et al. 'Computational 19 ? 2021
source	Homo sapiens
experiment	X-ray (resolution=2.46, R-factor=0.195)
structural superfamily	SMAD MH1 domain;
sequence family	MH1 domain;
multimeric complexes	6fzt_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6fzt_A interface=69,71,73,78, sslfsftspavkrllgwkqgdeeekwaekavdslvkklkkkkgamdeleralscpgqpskcvtiprslDgRlQvshrKglphviycrvwrwpdlqshhelkpleccefpfgskqkevcinpyhyrrvetpv
interface signature	DRQK

Estimated binding specificities ?

readout + contact

# IC=3.520 IC/col=0.880 n_of_columns=4

specificity:

A |   0  20  19   0
C |  96  19  76  96
G |   0  38   0   0
T |   0  19   1   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RGQA--KG   L         +-----------------------------3kmp_A    
                       +-1 
  --RGQAHTKG   L     +-2 +-----------------------------5x6g_A    
                     ! ! 
  DCRGQC--KG   L   +-3 +-----------------------------6tbz_A    
                   ! ! 
  ----QC--KG     --4 +-----------------------------5mey_A    
                   ! 
  --RGQC--KG   L   +-----------------------------5nm9_A

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updated Sat Jan 10 10:11:34 2026