5x6g_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF SMAD5-MH1/PALINDROMIC SBE DNA COMPLEX (Mothers against decapentaplegic homolog 5)
reference	Wang et al. 'Nucleic 43 9051 2015
source	Mus musculus
experiment	X-ray (resolution=3.05, R-factor=0.224)
structural superfamily	SMAD MH1 domain;
sequence family	MH1 domain;
multimeric complexes	3kmp_AB 5x6g_AB 5x6m_AB 5x6m_EF 6fzs_AB 6fzt_AB
redundant complexes	5x6h 5x6m
reference complex	6fzs_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5x6g_A interface=65,67,70,72, tspavkrllgwkqgdeeekwaekavdalvkklkkkkgameelekalsspgqpskcvtiprsldgRlQvsHrKglphviycrvwrwpdlqshhelkpldicefpfgskqkevcinpyhykrve
interface signature	RQHK

Estimated binding specificities ?

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# IC=5.300 IC/col=0.883 n_of_columns=6

specificity:

A |   0   9  11   0   0  67
C |   0  11   9  96   0   9
G |   0  67   9   0   0   9
T |  96   9  67   0  96  11

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Dendrogram of similar interfaces ?

matrix format

  
  --RGQAHTKG   L                 +--5x6g_A    
                   +-------------2 
  DCRGQC--KG   L   !             +--6tbz_A    
                 --3 
  ----QC--KG       !                +5mey_A    
                   +----------------1 
  --RGQC--KG   L                    +5nm9_A

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updated Thu Sep 12 22:16:28 2024