interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN TRANSCRIPTION FACTOR ERG, HUMAN RUNX2 BOUND TO CORE BINDING FACTOR BETA (CBFB), IN COMPLEX WITH 16MER DNA CAGAGGATGTGGCTTC
referenceTsodikov et al. Structure 29 404 2021
experimentX-ray (resolution=4.25, R-factor=0.313)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
multimeric complexes6vgd_AD 6vge_AD 6vgg_AD
reference complex6vgd_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVDR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.775 n_of_columns=4 specificity:   
A |   0   0  16  16
C |   0   0  13  13
G |  96   0  54  54
T |   0  96  13  13
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updated Tue Dec 17 07:35:11 2024