interface graph thumbnail
legend  pdf

structure nameOCT4/SOX2 PROTEIN:DNA COMPLEX
referenceChojnowski et al. 'To ? ? ?
experimentX-ray (resolution=3.14, R-factor=0.201)
structural superfamilylambda repressor-like DNA-binding domains;
sequence familyPou domain Nterminal to homeobox domain;
multimeric complexes3l1p_AB 6ht5_DE 8bx1_AE 8bx2_AE
reference complex8bx1_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQTSR

Estimated binding specificities ?

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# IC=6.231 IC/col=0.692 n_of_columns=9 specificity:   
A |   7  96   0  14   0   9  24  24   8
C |   7   0   0   7  96  14  24  24   0
G |   9   0   0  66   0   7  24  24   7
T |  73   0  96   9   0  66  24  24  81
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updated Sat Aug 2 23:09:17 2025