interface graph thumbnail
legend  pdf

structure nameOCT4/SOX2 PROTEIN:DNA COMPLEX
referenceChojnowski et al. 'To ? ? ?
experimentX-ray (resolution=3.14, R-factor=0.201)
structural superfamilylambda repressor-like DNA-binding domains;
sequence familyPou domain Nterminal to homeobox domain;
multimeric complexes3l1p_AB 6ht5_DE 8bx1_AE 8bx2_AE
reference complex8bx1_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQTSR

Estimated binding specificities ?

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# IC=6.377 IC/col=0.709 n_of_columns=9 specificity:   
A |  80  24  24  64   0   8  96   0  80
C |   8  24  24   8   0  64   0   0   0
G |   0  24  24   8  96   8   0   0   8
T |   8  24  24  16   0  16   0  96   8
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updated Tue Dec 17 15:49:09 2024