8scm_D : 3D-footprint complex

structure name	BST DNA POLYMERASE I LARGE FRAGMENT MUTANT F710Y/D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 8H (DNA polymerase I)
reference	Lelyveld et al. Science 382 423 2023
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=2.30, R-factor=0.196)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
sequence family	DNA polymerase family A;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8scm_D interface=235,255,257,285,289,290,318,325,328,361,406,410,413,417,496,500,532, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgKlqsTYiegllkvvrpatkkvhtifnqaltqtgRlsstepNlqNipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrRqakAvnYgivYgisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvHdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak
interface signature	KTYKTYRNNERAYYNQH

Estimated binding specificities ?

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# IC=5.766 IC/col=0.577 n_of_columns=10

specificity:

A |  96  24  24  24  24  13   0  96  13   0
C |   0  24  24  24  24  13  96   0  13   0
G |   0  24  24  24  24  16   0   0  54  96
T |   0  24  24  24  24  54   0   0  16   0

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updated Tue Dec 17 19:25:55 2024