interface graph thumbnail
legend  pdf

structure nameBST DNA POLYMERASE I LARGE FRAGMENT WILDTYPE D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 1H
(DNA polymerase I)
referenceLelyveld et al. Science 382 423 2023
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=2.08, R-factor=0.192)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A;
multimeric complexes8scg_AD 8sci_AD 8scj_AD 8sck_AD 8scl_AD 8scm_AD 8scn_AD 8sco_AD 8scp_AD 8scr_AD 8scs_AD 8sct_AD 8scu_AD
reference complex4yfu_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePKTYKTYRNNEFYNQH

Estimated binding specificities ?

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# IC=5.425 IC/col=0.543 n_of_columns=10 specificity:   
A |  96  24  24  24  24  10   0  85  10   0
C |   0  24  24  24  24  12  86  11  10   0
G |   0  24  24  24  24  10  10   0  64  96
T |   0  24  24  24  24  64   0   0  12   0
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updated Sun Aug 3 02:50:37 2025