8sct_D : 3D-footprint complex

structure name	BST DNA POLYMERASE I LARGE FRAGMENT WILDTYPE D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 24H (DNA polymerase I)
reference	Lelyveld et al. Science 382 423 2023
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=2.34, R-factor=0.189)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
sequence family	DNA polymerase family A;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sct_D interface=234,235,255,257,285,289,290,318,325,328,361,413,417,496,500,532, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninsPKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgKlqsTYiegllkvvrpatkkvhtifnqaltqtgRlsstepNlqNipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakavnFgivYgisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvHdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak
interface signature	PKTYKTYRNNEFYNQH

Estimated binding specificities ?

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# IC=5.807 IC/col=0.581 n_of_columns=10

specificity:

A |   0  16   0   0  57  24  24  24  24  96
C |   0  54   0   0  13  24  24  24  24   0
G |  96  13   0  96  13  24  24  24  24   0
T |   0  13  96   0  13  24  24  24  24   0

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updated Tue Dec 17 19:26:53 2024