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structure nameCRYSTAL STRUCTURE OF A ZIF23-GCN4 CHIMERA BOUND TO DNA
(CHIMERA OF ZIF23-GCN4)
referenceWolfe et al.
sourceMUS MUSCULUS, SACCHAROMYCES CEREVISIAE
experimentX-ray (resolution=1.50, R-factor=?)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
multimeric complexes1llm_CD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRDHTRDER

Estimated binding specificities ?

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# IC=8.885 IC/col=1.111 n_of_columns=8 specificity:   
A |   0   0   0  76   0   0   0  19
C |  96  96  96  20  96   0  96  20
G |   0   0   0   0   0  96   0  38
T |   0   0   0   0   0   0   0  19
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: GCN4
CACGTGPubMed1llm_D(7.45e-03), 1llm_CD(1.13e-03)
TTGCGTGAPubMed1llm_D(7.34e-04), 1llm_CD(6.36e-03)

Dendrogram of similar interfaces ?

matrix format
  
  RGST--YGYC----QC--TGST--RGYT           +-----------------------------4is1_C    
                                       +-4 
  --RG--DAQARG--RGSTDCHG----TT   L     ! +-----------------------------6b0o_A    
                                       ! 
  --EC--SCKGRG--LT--FCNA------   L   +-5                        +----1ubd_C    
                                     ! !                  +-----2 
  ----TCYCKARG--QA----TC------       ! !                  !     +----5yeg_A    
                                     ! +------------------3 
  --QA--TCNA----QAHTTT------QA   L --6                    !         +1g2d_F    
                                     !                    +---------1 
  --RGSTDAHARG--RGSTDCHG----TT   L   !                              +5kl3_A    
                                     ! 
  ----------NCAT------STRA----       +-----------------------------1a02_J    
                                   

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updated Fri Sep 13 15:47:57 2024