1lo1_A : 3D-footprint complex

structure name	ESTROGEN RELATED RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH DNA (STEROID HORMONE RECEPTOR ERR2)
source	HOMO SAPIENS
experiment	NMR
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	8ifo_AB
redundant complexes	8ifo_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1lo1_A interface=18,25,26,28,29,32,33,83,86, aipkrlclvcgdiasgyHygvascEAcKAffKRtiqgnieyscpatneceitkrrrkscqacrfmkalkvgmlkegvrldrvRggRqkyk
interface signature	HEAKAKRRR

Estimated binding specificities ?

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# IC=8.431 IC/col=0.843 n_of_columns=10

specificity:

A |  16  24  96   0   0   0  24   0  96  13
C |  13  24   0  96  96   0  24   0   0  13
G |  13  24   0   0   0   0  24  96   0  54
T |  54  24   0   0   0  96  24   0   0  16

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: ESTROGEN RECEPTOR
GGTGACCTTGACC	PubMed	1lo1_A(1.43e-03)
CATAACCTTGACC	PubMed	1lo1_A(1.43e-03)
TNAAGGTCA	PubMed	1lo1_A(7.43e-03)

Dendrogram of similar interfaces ?

matrix format

  
  CAECKG--KGRG--RTRT   L                          +----1cit_A    
                                    +-------------4 
  --EAKG--KTRG------   L            !             !    +4umm_A    
                                    !             +----1 
  ----KGVG--RG------   L     +------5                  +4tnt_B    
                             !      ! 
  --ECKGAGKGRG------   L     !      !                +-1hcq_E    
                             !      +----------------3 
  --ECKGAG--KTRG----   L   +-6                       ! +4aa6_B    
                           ! !                       +-2 
  ----KGVT--RG------   L   ! !                         +5emc_A    
                         --7 ! 
  ----KGVT--RG------   L   ! +-------------------------2c7a_B    
                           ! 
  --ECKGAG--RG------   L   +--------------------------4ond_A

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updated Mon Jun 29 14:24:23 2026