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structure nameESTROGEN RELATED RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH DNA
(STEROID HORMONE RECEPTOR ERR2)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes8ifo_AB
redundant complexes8ifo_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHEAKAKRRR

Estimated binding specificities ?

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# IC=8.431 IC/col=0.843 n_of_columns=10 specificity:   
A |  13  24  96   0   0   0  24   0  96  16
C |  16  24   0  96  96   0  24   0   0  13
G |  13  24   0   0   0   0  24  96   0  54
T |  54  24   0   0   0  96  24   0   0  13
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ESTROGEN RECEPTOR
GGTGACCTTGACCPubMed1lo1_A(1.43e-03)
CATAACCTTGACCPubMed1lo1_A(1.43e-03)
TNAAGGTCAPubMed1lo1_A(7.43e-03)

Dendrogram of similar interfaces ?

matrix format
  
  CAECKG--KGRG--RTRT   L                          +---1cit_A    
                                    +-------------2 
  --EAKG--KTRG------   L        +---3             +---4umm_A    
                                !   ! 
  ----KGVT--RG------   L   +----4   +-----------------2c7a_B    
                           !    ! 
  --ECKGAG--RG------   L --5    +---------------------4ond_A    
                           ! 
  --ECKGAGKGRG------   L   !                         +1hcq_E    
                           +-------------------------1 
  --ECKGAG--KTRG----   L                             +4aa6_B    
                         

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updated Sat Jan 10 04:47:07 2026