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legend  pdf

structure nameDNA COMPLEXED STRUCTURE OF THE KEY TRANSCRIPTION FACTOR INITIATING DEVELOPMENT IN SPORULATION BACTERIA
(Stage 0 sporulation protein A)
referenceVarughese et al. Structure 10 1041 2002
sourceBacillus subtilis
experimentX-ray (resolution=2.30, R-factor=0.218)
structural superfamilyC-terminal effector domain of the bipartite response regulators;
sequence familySporulation initiation factor Spo0A C termin;
multimeric complexes1lq1_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTSERRH

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |   0   0  57   0  54
C |  96   0  13  96  13
G |   0  96  13   0  16
T |   0   0  13   0  13
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: SPO0A
TGNCGAAPubMed1lq1_D(1.02e-03)
TGTCGTAPubMed1lq1_D(7.33e-07), 1lq1_AB(1.57e-03)
TTGTCGAAPubMed1lq1_D(1.69e-06), 1lq1_AB(6.39e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ------TT--SC--ECRG--RGHT   L               +---------------1lq1_D    
                                      +------1 
  ----------------NT------   L     +--2      +---------------1b72_B    
                                   !  ! 
  --------TTSGLTYART------   L   +-3  +----------------------2nra_C    
                                 ! ! 
  --------TCKTTCKGTCHTST--   L --4 +-------------------------7ve5_B    
                                 ! 
  RGRTKG------------------   L   +--------------------------6lui_A    
                               

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updated Fri Sep 13 15:48:28 2024