interface graph thumbnail
legend  pdf

structure nameC-TERMINAL DOMAIN OF VRAR
(DNA-binding response regulator)
referenceKumar et al. 'Protein 31 e4286 2022
sourceStaphylococcus aureus
experimentX-ray (resolution=2.00, R-factor=0.201)
structural superfamilyC-terminal effector domain of the bipartite response regulators;
sequence familyBacterial regulatory proteins, luxR fami; Sigma70, region 4;
multimeric complexes7ve5_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTKTKTHS

Estimated binding specificities ?

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# IC=6.207 IC/col=0.887 n_of_columns=7 specificity:   
A |  61   0   6  64   6   0  96
C |  13   0   6   6   6   0   0
G |   9  96   6  13   2  96   0
T |  13   0  78  13  82   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----KGTC--KGTCHT------------   L     +-----------------------------4wuh_B    
                                     +-4 
  ----SCTA--KTVCHT--KG--------   L   ! +-----------------------------1je8_F    
                                     ! 
  TC--KTTC--KGTCHT--ST--------   L --5                         +---7ve5_B    
                                     !          +--------------1 
  --ITKGTA--STSAQT------------   L   !      +---2              +---5w43_B    
                                     !      !   ! 
  DCLT----AG--TTRG------RG----   L   +------3   +------------------5h3r_A    
                                            ! 
  --------QTNAST--RGHTNT--STLA   L          +----------------------2hdc_A    
                                   

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updated Sat Sep 14 06:43:33 2024