1zq3_P : 3D-footprint complex

structure name	NMR SOLUTION STRUCTURE OF THE BICOID HOMEODOMAIN BOUND TO THE CONSENSUS DNA BINDING SITE TAATCC (HOMEOTIC BICOID PROTEIN)
source	DROSOPHILA MELANOGASTER
experiment	NMR
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1zq3_P interface=4,48,51,52,55,56, gprRtrttftssqiaeleqhflqgryltaprladlsaklalgtaqvkIwfKNrrRRhkiqsdqhkdqs
interface signature	RIKNRR

Estimated binding specificities ?

readout + contact

# IC=8.472 IC/col=1.059 n_of_columns=8

specificity:

A |  16   0   0  96  13   0  96   0
C |  13   0   0   0  13   0   0   0
G |  54  96  96   0  13   0   0  96
T |  13   0   0   0  57  96   0   0

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: BICOID
TAATCC	PubMed	1zq3_P(3.74e-09)
TAATCCC	PubMed	1zq3_P(1.48e-07)

Dendrogram of similar interfaces ?

matrix format

  
  --RTQTVAQTNA------   L                              +8osb_E    
                                      +---------------1 
  RART--VTKGNA--KA--   L            +-3               +2lkx_A    
                                    ! ! 
  ------NCICNARGRG--   L   +--------4 +---------------4xrm_B    
                           !        ! 
  --RT--IAQCNAMG----   L   !        !           +----1b72_A    
                         --5        +-----------2 
  --RC--IAQCNAYC----   L   !                    +----3rkq_B    
                           ! 
  ------------YCFAKC       +-------------------------6pe2_B

home
updated Fri Sep 13 16:10:08 2024