| structure name | CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX. (INTERFERON REGULATORY FACTOR 2) |
| reference | Taniguchi et al. 'EMBO 18 5028 1999 |
| source | Mus musculus |
| experiment | X-ray (resolution=2.20, R-factor=0.202) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Interferon regulatory factor transcription f; |
| multimeric complexes | 2irf_GH 2irf_IJKL |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | HKANRCNS |
Estimated binding specificities ?
| readout + contact |  |
A | 69 24 8 11 0 11 96 C | 11 24 0 8 0 8 0 G | 8 24 88 8 96 8 0 T | 8 24 0 69 0 69 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: IRF-2 | ||
| GAAAGT | PubMed | 2irf_IJKL(1.04e-03) |
| GAAAG | PubMed | 2irf_IJKL(7.85e-05) |
| AAGTGA | PubMed | 2irf_GH(1.03e-02), 2irf_IJKL(1.03e-03) |
Dendrogram of similar interfaces ?
matrix formatECKTRGAT--RGHT--RA L +---4mhg_A +-------------------------1 --KTRG----RGYT---- L +-2 +---4bqa_A ! ! ----NASTRGHT--ST-- L --3 +-----------------------------2uzk_A ! ----NASTRTHT--ST-- L +-----------------------------3l2c_A |
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updated Sun Aug 3 06:18:43 2025