| structure name | CRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO DBE1 DNA (Forkhead box protein O1) |
| reference | Marmorstein et al. Structure 16 1407 2008 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.10, R-factor=?) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Fork head domain; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | NSRHNSL |
Estimated binding specificities ?
| readout + contact |  |
A | 6 6 6 0 1 82 C | 6 23 6 0 6 0 G | 6 61 9 0 0 13 T | 78 6 75 96 89 1scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: FOXO1 | ||
| TGAGATGTTTTGAAAG | PubMed | 3co6_C(3.69e-04) |
| GTAAACAA | PubMed | 3co6_C(3.67e-09), 5dui_A(1.82e-03) |
| CAAAACA | PubMed | 3co6_C(6.27e-06) |
| AATAACA | PubMed | 3co6_C(3.38e-03) |
| ATAAACA | PubMed | 3co6_C(8.33e-10), 5dui_A(1.03e-03) |
| GTAAACA | PubMed | 3co6_C(8.33e-10), 5dui_A(1.03e-03) |
| CAAAACAAAACA | PubMed | 3co6_C(1.61e-04) |
Dendrogram of similar interfaces ?
matrix format--------NAST--RTHT--STLT-------- L +4lg0_A +-------------------------1 --------NAST--RGHT--STFT-------- L ! +1vtn_C ! --------NAST--RTHT--ST---------- L ! +---3l2c_A +-7 +------3 --------NAST--RGHT--STLT-------- L ! ! +------4 +---7cby_C ! ! ! ! TT--KATTQTTG----LTRT----KA--FT-- L ! ! +----5 +----------2p7c_B ! ! ! ! --------RGNT--RGSTAT--RA-------- L --8 +--6 +-----------------2o6g_G ! ! --RGSTRTSTHG------------------RA L ! ! +3zpl_B ! +---------------------2 ----------RC----YG--------KT---- ! +2acj_B ! ------KT--RGAT--RGNT------------ L +---------------------------8smh_F |
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updated Sat Jan 10 05:47:59 2026