| structure name | CRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO DBE1 DNA (Forkhead box protein O1) |
| reference | Marmorstein et al. Structure 16 1407 2008 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.10, R-factor=?) |
| structural superfamily | "Winged helix" DNA-binding domain; |
| sequence family | Fork head domain; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | NSRHNSL |
Estimated binding specificities ?
| readout + contact |  |
A | 7 7 7 0 1 88 C | 7 16 7 0 7 0 G | 7 66 9 0 0 8 T | 75 7 73 96 88 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: FOXO1 | ||
| TGAGATGTTTTGAAAG | PubMed | 3co6_C(3.69e-04) |
| GTAAACAA | PubMed | 3co6_C(3.67e-09), 5dui_A(1.82e-03) |
| CAAAACA | PubMed | 3co6_C(6.27e-06) |
| AATAACA | PubMed | 3co6_C(3.38e-03) |
| ATAAACA | PubMed | 3co6_C(8.33e-10), 5dui_A(1.03e-03) |
| GTAAACA | PubMed | 3co6_C(8.33e-10), 5dui_A(1.03e-03) |
| CAAAACAAAACA | PubMed | 3co6_C(1.61e-04) |
Dendrogram of similar interfaces ?
matrix format--------NAST--RTHT--STLT---------- L +4lg0_A +--------------------1 --------NAST--RGHT--STFT---------- L +------6 +1vtn_C ! ! --------------------------KGKG---- L ! +--------------------5xfq_A ! --------NAST--RTHT--ST------------ L ! +---3l2c_A ! +------3 --------NAST--RGHT--STLT---------- L --9 +------4 +---7cby_C ! ! ! TT--KATTQTTG----LTRT----KA----FT-- L ! +----5 +----------2p7c_B ! ! ! --------RGNT--RGSTAT--RA---------- L ! +----7 +-----------------2o6g_G ! ! ! --RGSTRTSTHG--------------------RA L ! ! ! +-3zpl_B +-8 +--------------------2 ----------RC----YG--------KT------ ! +-2acj_B ! ------KT--RGAT--RGNT-------------- L +---------------------------8smh_F |
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updated Mon Jun 29 15:57:16 2026